SMOC has developed a set of mouse models expressing humanized immune checkpoints. These models are suitable to assess the efficacy of drugs targeting immune checkpoints in fully immunocompetent mice.
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系統名：C57BL/6Smoc-Sirpatm2(hSIRPA)Cd274em1(hCD274)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-2000099
応用分野：Immunotherapy,cancer research,drug screening
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系統名：C57BL/6Smoc-Tmem173tm1(hTMem173)Cd274em1(hCD274)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-2000105
応用分野：Immunotherapy,cancer research,drug screening
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系統名：C57BL/6Smoc-Cd274em1(hPD-L1)Tigitem1(hTIGIT)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-18013
応用分野：Immunotherapy,cancer research,drug screening
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系統名：C57BL/6Smoc-Cd274em1(hPD-L1)Havcr2em1(hHAVCR2)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-190056
応用分野：Immunotherapy,cancer research,drug screening
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系統名：C57BL/6Smoc-Visrem1(hVSIR)Cd274em1(hCD274)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-2000094
応用分野：Immunotherapy,cancer research,drug screening
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系統名：C57BL/6Smoc-Selplgem1(hSELPLG)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-00046
応用分野：Immunotherapy,cancer research,drug screening
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系統名：C57BL/6Smoc-Selplgem2(hSELPLG)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-210026
応用分野：inmmue therapy；drug screening
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系統名：C57BL/6Smoc-Pvrigem1(hPVRIG)/Smoc
維持形態：Repository Live | SMOC番号：NM-HU-210008
応用分野：drug screening
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系統名：C57BL/6Smoc-Siglecgtm1(hSIGLEC10)/Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-2000061
応用分野：Immunotherapy,drug screening
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系統名：C57BL/6Smoc-Siglec15em1(hSIGLEC15)Smoc
維持形態：Repository Live | SMOC番号：NM-HU-190037
応用分野：Immunotherapy,cancer research,drug screening
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