SMOC has developed a set of mouse models expressing humanized immune checkpoints. These models are suitable to assess the efficacy of drugs targeting immune checkpoints in fully immunocompetent mice.
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系統名：C57BL/6Smoc-Pdcd1lg2em1(hPDCD1LG2)Pdcd1em1(hPDCD1)Cd274em1(hPD-L1)/Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-190060
応用分野：Immunotherapy,cancer research,drug screening
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系統名：C57BL/6Smoc-Pdcd1em1(hPDCD1)Cd274em1(hPD-L1)Tigitem1(hTIGIT)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-200267
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系統名：C57BL/6Smoc-Pdcd1em1(hPDCD1)Cd274em1(hPD-L1)Havcr2em1(hHAVCR2)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-200264
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系統名：C57BL/6Smoc-Pdcd1em1(hPDCD1) Pvrigem1(hPVRIG)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-231147
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系統名：C57BL/6Smoc-Pdcd1em1(hPDCD1)Sema4dem1(hSemA4D)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-190033
応用分野：Immunotherapy,cancer research,drug screening
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系統名：C57BL/6Smoc-Pdcd1em1(hPDCD1)Siglec15em1(hSIGLEC15)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-2000093
応用分野：Immunotherapy,cancer research,drug screening
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系統名：C57BL/6Smoc-Pdcd1em1(hPDCD1)Sirpatm2(hSIRPA)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-2000089
応用分野：Immunotherapy,drug screening
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系統名：C57BL/6Smoc-Tmem173tm1(hTMem173)Pdcd1em1(hPDCD1)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-2000104
応用分野：Immunotherapy,cancer research,drug screening
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系統名：C57BL/6Smoc-Pdcd1em1(hPDCD1) Tigitem1(hTIGIT)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-00104
応用分野：Immunotherapy,cancer research,drug screening
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系統名：C57BL/6Smoc-Pdcd1em1(hPDCD1)Tigitem1(hTIGIT) Havcr2em1(hHAVCR2)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-190029
応用分野：Immune-related
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