SMOC has developed a set of mouse models expressing humanized immune checkpoints. These models are suitable to assess the efficacy of drugs targeting immune checkpoints in fully immunocompetent mice.
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系統名：C57BL/6Smoc-Pdcd1em1(hPDCD1)Tnfrsf4em3(hTNFRSF4) Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-00108
応用分野：cancer research,Immunotherapy,drug screening
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系統名：C57BL/6Smoc-Pdcd1em1(hPDCD1)Cd274em1(hPD-L1)Smoc
維持形態：Repository Live | SMOC番号：NM-HU-00100
応用分野：Immunotherapy,cancer research,drug screening
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系統名：C57BL/6Smoc-Pdcd1em1(hPDCD1)Cd274em2(hPD-L1)Ccr8em1(hCCR8)/Smoc
維持形態：Developing | SMOC番号：NM-HU-210402
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系統名：BALB/cAnSmoc-Pdcd1em(hPDCD1)Cd274em(hPD-L1)/Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-220142
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系統名：BALB/cAnSmoc-Pdcd1em(hPDCD1)Cd274em(hPD-L1)Sirpatm4(hSIRPA)Cd47em1(hCD47)/Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-220143
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系統名：C57BL/6Smoc-Pdcd1em1(hPD-1)Cd274em1(hPD-L1)Nt5eem2(hNT5E)/Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-210410
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系統名：C57BL/6Smoc-Pdcd1em1(hPD-1)Cd274em1(hPD-L1)Ctla4em1(hCTLA4)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-200266
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系統名：C57BL/6Smoc-Ido1tm1(hIDO1)Pdcd1em1(hPDCD1)Cd274em1(hPD-L1)Smoc
維持形態：Developing | SMOC番号：NM-HU-00120
応用分野：cancer research,Immunotherapy,drug screening
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系統名：C57BL/6Smoc-Pdcd1em1(hPDCD1)Cd274em1(hPD-L1)Lag3em1(hLAG3)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-190028
応用分野：Immune-related
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系統名：C57BL/6Smoc-Tnfrsf4em3(hTNFRSF4)Pdcd1em1(hPDCD1)Cd274em1(hPD-L1)Smoc
維持形態：Repository Live | SMOC番号：NM-HU-00122
応用分野：Immunotherapy,cancer research,drug screening
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