SMOC has developed a set of mouse models expressing humanized immune checkpoints. These models are suitable to assess the efficacy of drugs targeting immune checkpoints in fully immunocompetent mice.
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系統名：C57BL/6Smoc-Pdcd1em1(hPDCD1)Havcr2em1(hHAVCR2)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-00103
応用分野：Immunotherapy,cancer research,drug screening
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系統名：C57BL/6Smoc-Pdcd1em1(hPDCD1)Tlr9 tm1(hTLR9)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-190023
応用分野：Immune-related
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系統名：C57BL/6Smoc-Pdcd1em1(hPDCD1)Kdrtm2(hKDR)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-2000098
応用分野：Immunotherapy,cancer research,drug screening
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系統名：C57BL/6Smoc-Visrem1(hVSIR)Pdcd1em1(hPDCD1)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-2000092
応用分野：Immunotherapy,cancer research,drug screening
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系統名：C57BL/6Smoc-Cd274em1(hPD-L1)Tnfrsf9tm2(h4-1BB)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-200260
応用分野：umor research；inmmue therapy；drug screening
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系統名：C57BL/6Smoc-Cd274em1(hPD-L1)Cd40em1(hCD40)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-18024
応用分野：Immunotherapy,cancer research,drug screening
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系統名：C57BL/6Smoc-Ctla4em1(hCTLA4)Cd274em1(hPD-L1)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-00102
応用分野：Immunotherapy,cancer research,drug screening
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系統名：C57BL/6Smoc-Cd274em1(hPD-L1)Lag3tm1(hLAG3)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-00137
応用分野：Immunotherapy,cancer research,drug screening
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系統名：C57BL/6Smoc-Cd274em1(hPD-L1)Tnfrsf4em1(hTNFRSF4)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-00111
応用分野：cancer research,Immunotherapy,drug screening
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系統名：C57BL/6Smoc-Cd274em1(hCD274)Siglec15em1(hSIGLEC15)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-2000103
応用分野：Immunotherapy,cancer research,drug screening
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