Humanized tumor target mice are immunocompetent chimeric mouse models, engineered to express humanized tumor targets such as genes encoding for oncogene proteins, tumor suppressor proteins, tumor specific antigen, etc. These models can can be used to evaluate the risk of on-target, off-tumor toxicities for targeted cancer drug.
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系統名：C57BL/6Smoc-Igs2em1(CAG-loxp-Neo-Stop-loxp-lox2272-Neo-Stop-lox2272-HA tag-NMYC-IRES-EFGP-WPRE-polyA)Smoc
維持形態：Sperm cryopreservation | SMOC番号：NM-KI-210145
応用分野：Cancer research
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系統名：BALB/cAnSmoc-Ccr8em(hCCR8)Smoc
維持形態：Sperm cryopreservation | SMOC番号：NM-HU-220501
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