The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.
|
|
系統名：C57BL/6Smoc-Apoc3tm1(pAlb-hREN-WPRE-pA)Smoc
維持形態：Repository Live | SMOC番号：NM-KI-235088
|
|
|
|
系統名：C57BL/6Smoc-Avilem1(LSL-Kozak-hM3Dq-mCherry-WPRE-pA)Smoc
維持形態：Sperm cryopreservation | SMOC番号：NM-KI-232881
|
|
|
|
系統名：C57BL/6Smoc-Tgtn(CAG-human ACE2-IRES-Luciferase-WPRE-polyA)Smoc
維持形態：Repository Live | SMOC番号：NM-TG-200002
応用分野：corona virus related research
|
|
|
|
系統名：C57BL/6Smoc-Igs2em1(CAG-LSL-ACHE-WPRE-pA)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-KI-00067
応用分野：Cholinesterase related drug research
|
|
|
|
系統名：C57BL/6Smoc-Igs2em1(CAG-loxP-STOP-loxP-hHTTQ148-hHTT 3'UTR-pA)Smoc
維持形態：Developing | SMOC番号：NM-KI-234493
|
|
|
|
系統名：C57BL/6Smoc-Igs2em1(CAG-loxP-STOP-loxP-hLILRB4-IRES-EGFP-WPRE-pA)Smoc
維持形態：Sperm cryopreservation | SMOC番号：NM-KI-230387
|
|
|
|
系統名：C57BL/6Smoc-Igs2em1(CAG-LSL-PSEN1-IRES-tdTomato-WPRE-polyA)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-KI-190110
応用分野：Alzheimer's research
|
|
|
|
系統名：C57BL/6Smoc-Igs2em1(CAG-loxp-Neo-Stop-loxp-lox2272-Neo-Stop-lox2272-HA tag-NMYC-IRES-EFGP-WPRE-polyA)Smoc
維持形態：Sperm cryopreservation | SMOC番号：NM-KI-210145
応用分野：Cancer research
|
|
|
|
系統名：C57BL/6Smoc-Igs2em1(ALB promoter-human ALB-IRES-Luciferase-polyA)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-KI-200322
|
|
|
|
系統名：C57BL/6Smoc-Igs2em1(pAlb-hBAFF-pA)Smoc
維持形態：Sperm cryopreservation | SMOC番号：NM-KI-232137
|
