The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.
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系統名：C57BL/6Smoc-Gt(ROSA)26Sortm1(SA-Frt-2xpolyA-CAG-Frt-LSL-TM6SF2-IRES-GFP-WPRE-PA)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-KI-200017
応用分野：Non-alcoholic fatty liver disease
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系統名：C57BL/6Smoc-Gt(ROSA)26Sortm(SA-polyA-CAG-LSL-TPM3-NTRK1-IRES-luc-2A-tdTomato-WPRE-polyA)Smoc
維持形態：Sperm cryopreservation | SMOC番号：NM-KI-190098
応用分野：Colorectal carcinoma related.
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系統名：BALB/cAnSmoc-Gt(ROSA)26Sortm1(CAG-loxP-STOP-lox2272-hTSHRa-loxP-lox2272-WPRE-pA)Smoc
維持形態：Sperm cryopreservation | SMOC番号：NM-KI-234654
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系統名：C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-FRT-2xpA-CAG-FRT-loxp-STOP-loxp-WNT1-IRES-Luciferase-2A-tdTomato-WPRE-polyA)Smoc
維持形態：Sperm cryopreservation | SMOC番号：NM-KI-190128
応用分野：Wnt1 signaling pathway, cancer research, etc
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系統名：C57BL/6Smoc-Gt(ROSA)26Sorem(CAG-LSL-SOX2-IRES-Luciferase-2a-EGFP-WPRE-polyA)Smoc
維持形態：Sperm cryopreservation | SMOC番号：NM-KI-210138
応用分野：Fluorescent reporter Mice
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系統名：C57BL/6Smoc-Gt(ROSA)26Sortm1(SA-hCD46-IRES-tdTomato-polyA)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-KI-190087
応用分野：Immune-related
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系統名：C57BL/6Smoc-Gt(ROSA)26Sortm1(CAG-LSL-EZH2-IRES-luciferase-2A-tdTomato)Smoc
維持形態：Sperm cryopreservation | SMOC番号：NM-KI-18053
応用分野：Tumor research; drug screening
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系統名：C57BL/6Smoc-Gt(ROSA)26Sortm1(CAG-LSL-Kozak-hIGF1R-IRES-EGFP-WPRE-pA)Smoc
維持形態：Sperm cryopreservation | SMOC番号：NM-KI-231795
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系統名：C57BL/6Smoc-Gt(ROSA)26Sortm(CAG-Loxp-Stop-Loxp-Kozak-hIL2 signal peptide-hIL15-Flag-IRES-EGFP-polyA)Smoc
維持形態：Sperm cryopreservation | SMOC番号：NM-KI-220130
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系統名：C57BL/6Smoc-Gt(ROSA)26Sortm1(SA-LSL-Kozak-hNTN1-WPRE-pA)Smoc
維持形態：Sperm cryopreservation | SMOC番号：NM-KI-233967
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