The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.
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系統名：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-IDH1(R132H)-IRES-Luciferase-2A-tdTomato)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-KI-190074
応用分野：cancer research
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系統名：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-IDH2(R140Q)-IRES-Luciferase-2A-tdTomato)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-KI-190075
病気の予測：D-2-hydroxyglutaric aciduria
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系統名：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-IDH2(R172K)-IRES-Luciferase-2A-tdTomato)Smoc
維持形態：Sperm cryopreservation | SMOC番号：NM-KI-190076
応用分野：cancer research
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系統名：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-c-MET-IRES-luciferase-2A-tdTomato)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-KI-18052
応用分野：Tumor research; drug screening
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系統名：C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-FRT-2xpA-CAG-FRT-loxp-STOP-loxp-MLL-AF9-IRES-Luciferase-2A-tdTomato -WPRE-polyA)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-KI-190114
応用分野：Acute myelogenous leukemia model
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系統名：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-hMSLN-IRES-Luciferase-WPRE-pA)Smoc
維持形態：Sperm cryopreservation | SMOC番号：NM-KI-225094
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系統名：C57BL/6Smoc-Gt(ROSA)26Sorem(CAG-LSL-HA-hMYCN-IRES-BFP-Wpre-polyA)1Smoc
維持形態：Sperm cryopreservation | SMOC番号：NM-KI-225000
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系統名：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-NFE2L2(G81S)-IRES-Luciferase-2A-tdTomato)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-KI-190077
応用分野：cancer research
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系統名：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-NRF2-IRES-luciferase-2A-tdTomato)Smoc
維持形態：Sperm cryopreservation | SMOC番号：NM-KI-18050
応用分野：Tumor research; drug screening
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系統名：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-PIK3CA(H1047R)-IRES-luciferase-2A-tdTomato)Smoc
維持形態：Repository Live | SMOC番号：NM-KI-190065
病気の予測：breast cancer, CLOVES syndrome, ovarian cancer, brain glioma
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