The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.
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系統名：C57BL/6Smoc-Igs2em1(pAlb-hHAO1 CDS-hHAO1 3'UTR-pA)Smoc
維持形態：Sperm cryopreservation | SMOC番号：NM-KI-231910
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系統名：C57BL/6Smoc-Igs2em(pK18-hACE2)1Smoc
維持形態：Sperm cryopreservation | SMOC番号：NM-KI-225001
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系統名：C57BL/6Smoc-Igs2em(pT3(b)-Kozak-hIL2 signal peptide-hIL15-Flag-polyA-pT3(b)-Kozak-hIL2 signal peptide-hIL15-Flag-polyA)Smoc
維持形態：Sperm cryopreservation | SMOC番号：NM-KI-220128
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系統名：C57BL/6Smoc-Igs2em1(pThy1-PSEN1-IRES-tdTomato-WPRE-pA)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-KI-18049
応用分野：Alzheimer's research
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系統名：FVB-Igs2em1(rIns1-Cre-WPRE-pA-Insulator-Insulator-CAG-loxP-STOP-loxP-hGAST-WPRE-pA)Smoc
維持形態：Developing | SMOC番号：NM-KI-240016
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系統名：C57BL/6Smoc-Tnfrsf9tm2(TNFRSF9)Smoc
維持形態：Repository Live | SMOC番号：NM-HU-190077
応用分野：Immunotherapy,Cancer research,Drug screening
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系統名：C57BL/6Smoc-Tnfrsf9tm2(TNFRSF9)Cd3eem2(hCD3E)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-210409
応用分野：Drug Screening; Immunotherapy Evaluation
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系統名：C57BL/6Smoc-Tnfrsf9tm2(TNFRSF9)Tnfrsf4em1(hTNFRSF4)/Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-200272
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系統名：C57BL/6Smoc-Tnfrsf9tm2(h4-1BB)Pdcd1em1(hPDCD1)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-200279
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系統名：C57BL/6Smoc-Tnfrsf9tm2(TNFRSF9)Pdcd1em1(hPDCD1)Cd274em1(hPD-L1)/Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-210357
応用分野：inmmue therapy；drug screening
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