The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.
|
|
系統名：C57BL/6Smoc-Gt(ROSA)26Sorem(CAG-LSL-hPLA2R1-IRES-EGFP)Smoc
維持形態：Repository Live | SMOC番号：NM-KI-220264
|
|
|
|
系統名：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-hPLAG1-IRES-Luciferase-2A-tdTomato-wpre-polyA)Smoc
維持形態：Sperm cryopreservation | SMOC番号：NM-KI-215002
|
|
|
|
系統名：C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-Frt-2xpolyA-CAG-Frt-LSL-hPNPLA3 I148M-IRES-GFP-wpre-polyA)Smoc
維持形態：Repository Live | SMOC番号：NM-KI-200013
応用分野：rs738409：148 isoleucine to Methionine protein variant,I148M.Non-alcoholic fatty liver and hepatitis B cirrhosis research.
|
|
|
|
系統名：C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-FRT-2xpA-CAG-FRT-LSL-Kozak-hPROCR-WPRE-pA)Smoc
維持形態：Developing | SMOC番号：NM-KI-240013
|
|
|
|
系統名：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-REST-IRES-tdTomato-WPRE-polyA)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-KI-200051
応用分野：Cancer and aging research
|
|
|
|
系統名：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-REST4-IRES-EGFP-WPRE-polyA)Smoc
維持形態：Sperm cryopreservation | SMOC番号：NM-KI-200052
|
|
|
|
系統名：C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-FRT-2xpolyA-CAG-FRT-LSL-RHOA(Y42C)-IRES-tdTomato-WPRE-polyA)Smoc
維持形態：Sperm cryopreservation | SMOC番号：NM-KI-200048
応用分野：Cancer research
|
|
|
|
系統名：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-SIGLEC8-IRES-EGFP-WPRE-polyA)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-KI-210137
応用分野：Fluorescent reporter Mice
|
|
|
|
系統名：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-SNCA A53T-IRES-EGFP-WPRE-polyA)Smoc
維持形態：Sperm cryopreservation | SMOC番号：NM-KI-200320
|
|
|
|
系統名：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-FRT-LSL- SOD1(G94A)-IRES-EGFP-WPRE-pA)Smoc
維持形態：Sperm cryopreservation | SMOC番号：NM-KI-200263
病気の予測：amyotrophic lateral sclerosis type 1
|
