Humanized tumor target mice are immunocompetent chimeric mouse models, engineered to express humanized tumor targets such as genes encoding for oncogene proteins, tumor suppressor proteins, tumor specific antigen, etc. These models can can be used to evaluate the risk of on-target, off-tumor toxicities for targeted cancer drug.
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系統名：C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-FRT-2xpA-CAG-FRT-loxp-STOP-loxp-WNT1-IRES-Luciferase-2A-tdTomato-WPRE-polyA)Smoc
維持形態：Sperm cryopreservation | SMOC番号：NM-KI-190128
応用分野：Wnt1 signaling pathway, cancer research, etc
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系統名：C57BL/6Smoc-Gt(ROSA)26Sorem(CAG-LSL-SOX2-IRES-Luciferase-2a-EGFP-WPRE-polyA)Smoc
維持形態：Sperm cryopreservation | SMOC番号：NM-KI-210138
応用分野：Fluorescent reporter Mice
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系統名：C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-hCD46-IRES-tdTomato-polyA)Smoc
維持形態：Repository Live | SMOC番号：NM-KI-190087
応用分野：Immune-related
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系統名：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-EZH2-IRES-luciferase-2A-tdTomato)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-KI-18053
応用分野：Tumor research; drug screening
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系統名：C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-LSL-Kozak-hNTN1-WPRE-pA)Smoc
維持形態：Sperm cryopreservation | SMOC番号：NM-KI-233967
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系統名：C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-loxp-stop-loxp-hMycRTG3-ERT2-IRES-EGFP-WPRE-pA)Smoc
維持形態：Sperm cryopreservation | SMOC番号：NM-KI-225096
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系統名：C57BL/6Smoc-Rab31em1(hRAB31*Y76F/Y86F/Y137F)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-KI-210419
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系統名：C57BL/6Smoc-Kdrtm2(hKDR)Rag2em1Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-200280
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系統名：C57BL/6Smoc-Il2rgem1Kdrtm2(hKDR)Rag2em1Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-220087
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系統名：C57BL/6Smoc-Igs7em1(tetO-EGFR-del19-IRES-GFP-2A-Cre)Smoc
維持形態：Sperm cryopreservation | SMOC番号：NM-KI-200258
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