Humanized tumor target mice are immunocompetent chimeric mouse models, engineered to express humanized tumor targets such as genes encoding for oncogene proteins, tumor suppressor proteins, tumor specific antigen, etc. These models can can be used to evaluate the risk of on-target, off-tumor toxicities for targeted cancer drug.
|
|
系統名：C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-2xpolyA-CAG-LSL-EML4-ALK(F1174L)-IRES-luciferase-2A-tdTomato)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-KI-190010
応用分野：cancer
|
|
|
|
系統名：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-emL4-ALK-IRES-Luciferase-2A-tdTomato)Smoc
維持形態：Sperm cryopreservation | SMOC番号：NM-KI-190072
応用分野：cancer research
|
|
|
|
系統名：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-EZH2(Y646N)-IRES-Luciferase-2A-tdTomato)Smoc
維持形態：Repository Live | SMOC番号：NM-KI-190073
応用分野：cancer research
|
|
|
|
系統名：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-ERBB2(exon20 insertion)-IRES-Luciferase-2A-EGFP)Smoc
維持形態：Sperm cryopreservation | SMOC番号：NM-KI-190071
応用分野：cancer research
|
|
|
|
系統名：C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-2xpolyA-CAG-LSL-HER2-luciferase-EGFP)Smoc
維持形態：Sperm cryopreservation | SMOC番号：NM-KI-190008
応用分野：cancer
|
|
|
|
系統名：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-IDH2(R140Q)-IRES-Luciferase-2A-tdTomato)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-KI-190075
病気の予測：D-2-hydroxyglutaric aciduria
|
|
|
|
系統名：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-IDH2(R172K)-IRES-Luciferase-2A-tdTomato)Smoc
維持形態：Sperm cryopreservation | SMOC番号：NM-KI-190076
応用分野：cancer research
|
|
|
|
系統名：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-c-MET-IRES-luciferase-2A-tdTomato)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-KI-18052
応用分野：Tumor research; drug screening
|
|
|
|
系統名：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-hMSLN-IRES-Luciferase-WPRE-pA)Smoc
維持形態：Sperm cryopreservation | SMOC番号：NM-KI-225094
|
|
|
|
系統名：C57BL/6Smoc-Gt(ROSA)26Sorem(CAG-LSL-HA-hMYCN-IRES-BFP-Wpre-polyA)1Smoc
維持形態：Sperm cryopreservation | SMOC番号：NM-KI-225000
|
