Humanized tumor target mice are immunocompetent chimeric mouse models, engineered to express humanized tumor targets such as genes encoding for oncogene proteins, tumor suppressor proteins, tumor specific antigen, etc. These models can can be used to evaluate the risk of on-target, off-tumor toxicities for targeted cancer drug.
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系統名：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-NFE2L2(G81S)-IRES-Luciferase-2A-tdTomato)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-KI-190077
応用分野：cancer research
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系統名：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-NRF2-IRES-luciferase-2A-tdTomato)Smoc
維持形態：Sperm cryopreservation | SMOC番号：NM-KI-18050
応用分野：Tumor research; drug screening
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系統名：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-PIK3CA(H1047R)-IRES-luciferase-2A-tdTomato)Smoc
維持形態：Repository Live | SMOC番号：NM-KI-190065
病気の予測：breast cancer, CLOVES syndrome, ovarian cancer, brain glioma
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系統名：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-hPLAG1-IRES-Luciferase-2A-tdTomato-wpre-polyA)Smoc
維持形態：Sperm cryopreservation | SMOC番号：NM-KI-215002
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系統名：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-REST-IRES-tdTomato-WPRE-polyA)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-KI-200051
応用分野：Cancer and aging research
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系統名：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-REST4-IRES-EGFP-WPRE-polyA)Smoc
維持形態：Sperm cryopreservation | SMOC番号：NM-KI-200052
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系統名：C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-FRT-2xpolyA-CAG-FRT-LSL-RHOA(Y42C)-IRES-tdTomato-WPRE-polyA)Smoc
維持形態：Sperm cryopreservation | SMOC番号：NM-KI-200048
応用分野：Cancer research
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系統名：C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-FRT-2xpolyA-CAG-FRT-loxp-Stop-loxp-SOS-F-IRES-tdTomato-WPRE-PA)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-KI-200020
応用分野：Spontaneous skin cancer model
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系統名：C57BL/6Smoc-Gt(ROSA)26Sorem(CAG-LSL-SOX2-IRES-Luciferase-2a-EGFP-WPRE-polyA)Krasem4(LSL-G12D)Smoc
維持形態：Sperm cryopreservation | SMOC番号：NM-KI-234153
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系統名：C57BL/6Smoc-Gt(ROSA)26Sorem(SA-polyA-CAG-LSL-TPM3-NTRK1-IRES-luc-2A-tdTomato-WPRE-polyA)Smoc
維持形態：Sperm cryopreservation | SMOC番号：NM-KI-190098
応用分野：Colorectal carcinoma related.
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