Humanized tumor target mice are immunocompetent chimeric mouse models, engineered to express humanized tumor targets such as genes encoding for oncogene proteins, tumor suppressor proteins, tumor specific antigen, etc. These models can can be used to evaluate the risk of on-target, off-tumor toxicities for targeted cancer drug.
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系統名：C57BL/6Smoc-Mertkem1(hMERTK)/Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-2000031
応用分野：Immunotherapy,drug screening
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系統名：C57BL/6Smoc-Muc1tm(hMUC1-c.462insC)Smoc
維持形態：Repository Live | SMOC番号：NM-HU-220410
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系統名：C57BL/6Smoc-Nectin4tm1(hNECTIN4)/Smoc
維持形態：Repository Live | SMOC番号：NM-HU-210016
応用分野：drug screening
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