SMOC has developed a set of mouse models expressing humanized immune checkpoints. These models are suitable to assess the efficacy of drugs targeting immune checkpoints in fully immunocompetent mice.
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系統名：C57BL/6Smoc-Cd276tm2(hCD276)Pdcd1em1(hPDCD1)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-210349
応用分野：inmmue therapy；drug screening
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系統名：C57BL/6Smoc-Vtcn1em1(hVTCN1)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-190004
応用分野：Immune-related
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系統名：C57BL/6Smoc-Vtcn1em2(hVTCN1)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-190075
応用分野：Immunotherapy,Cancer research,Drug screening
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系統名：C57BL/6Smoc-Btlaem2(hBTLA)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-190040
応用分野：Immunotherapy,cancer research,drug screening
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系統名：BALB/cAnSmoc-Btlaem1(hBTLA)/Smoc
維持形態：Developing | SMOC番号：NM-HU-2000044
応用分野：Immunotherapy,drug screening
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系統名：C57BL/6Smoc-Ccr8em3(hCCR8)Ctla4em1(hCTLA4)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-220074
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系統名：C57BL/6Smoc-Tigittm3(hTIGIT)Ccr8em3(hCCR8)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-220073
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系統名：C57BL/6Smoc-Ccr8em1(hCCR8)Ctla4em1(hCTLA4)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-210435
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系統名：C57BL/6Smoc-Ccr8em1(hCCR8)Pdcd1em1(hPDCD1)/Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-210400
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系統名：C57BL/6Smoc-Bsgtm1(hBSG)/Smoc
維持形態：Repository Live | SMOC番号：NM-HU-2000021
応用分野：Immunotherapy,drug screening
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