SMOC has developed a set of mouse models expressing humanized immune checkpoints. These models are suitable to assess the efficacy of drugs targeting immune checkpoints in fully immunocompetent mice.
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系統名：C57BL/6Smoc-Cd22em2(hCD22)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-2000014
応用分野：Immunotherapy,cancer research,drug screening
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系統名：C57BL/6Smoc-Cd24aem1(hCD24-flox)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-231034
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系統名：C57BL/6Smoc-Cd24atm1(hCD24)Siglecgtm1(hSIGLEC10)Smoc
維持形態：Repository Live | SMOC番号：NM-HU-210367
応用分野：inmmue therapy;drug screening
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系統名：C57BL/6Smoc-Cd27tm3(hCD27)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-190035
応用分野：Immunotherapy,cancer research,drug screening
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系統名：C57BL/6Smoc-Cd27tm3(hCD27)Fcgrt2bem2(hFCGRT2B)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-210405
応用分野：inmmue therapy; drug screening
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系統名：BALB/cAnSmoc-Cd27tm(hCD27)Pdcd1em(hPD-1)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-220339
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系統名：BALB/cAnSmoc-Cd27tm(hCD27)Cd274em(hPD-L1)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-220340
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