SMOC has developed a set of mouse models expressing humanized immune checkpoints. These models are suitable to assess the efficacy of drugs targeting immune checkpoints in fully immunocompetent mice.
|
|
系統名：C57BL/6Smoc-Tlr8tm2(TLR8)Pdcd1em1(hPDCD1)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-200276
|
|
|
|
系統名：C57BL/6Smoc-Lyz2em3(IRES-DTREGFP)Tlr8tm2(TLR8)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-200259
応用分野：tumor research；inmmue therapy；drug screening;myeloid cell-specific DTR mice
|
|
|
|
系統名：C57BL/6Smoc-Tlr9tm1(hTLR9)Smoc
維持形態：Repository Live | SMOC番号：NM-HU-18016
応用分野：drug screening
|
|
|
|
系統名：C57BL/6Smoc-Tlr9tm1(hTLR9)Tnfrsf4em3(hTNFRSF4)/Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-190024
応用分野：Immune-related
|
|
|
|
系統名：C57BL/6Smoc-Tnfrsf1bem2(hTNFRSF1B)Pdcd1em1(hPDCD1)Cd274em1(hPD-L1)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-220041
|
|
|
|
||
|
|
系統名：C57BL/6Smoc-Trem2em4(hTRem2)/Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-2000083
応用分野：Alzheimer's disease research;drug screening
|
|
|
|
系統名：C57BL/6Smoc-Vsirem1(hVSIR)/Smoc
維持形態：Repository Live | SMOC番号：NM-HU-00118
応用分野：Immunotherapy,cancer research,drug screening
|
|
|
|
系統名：C57BL/6Smoc-Vsig4em1(hVSIG4)/Smoc
維持形態：Sperm cryopreservation | SMOC番号：NM-HU-210004
応用分野：inmmue therapy；drug screening
|
|
|
|
系統名：C57BL/6Smoc-Ighmem1Ighdem1Sirpaem1(hSIRPA)Cd47em1(hCD47)/Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-232159
|
