SMOC has developed a set of mouse models expressing humanized immune checkpoints. These models are suitable to assess the efficacy of drugs targeting immune checkpoints in fully immunocompetent mice.
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系統名：C57BL/6Smoc-Sirpatm2(hSIRPA)Cd274em1(hCD274)Cd47em1(hCD47)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-2000095
応用分野：Immunotherapy,cancer research,drug screening
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系統名：BALB/cAnSmoc-Sirpatm(hSIRPA)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-210369
応用分野：inmmue therapy;drug screening
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系統名：BALB/cAnSmoc-Sirpatm4(hSIRPA)/SmocCd47em1(hCD47)/Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-210020
応用分野：tumor research；inmmue therapy；drug screening
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系統名：C57BL/6Smoc-Slamf7em(hSLAMF7)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-18028
応用分野：Immunotherapy,Cancer research,Drug screening
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系統名：C57BL/6Smoc-Tmem173tm2(hTMEM173)Smoc
維持形態：Repository Live | SMOC番号：NM-HU-190036
応用分野：Immunotherapy,cancer research,drug screening
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系統名：BALB/cAnSmoc-tmem173tm1(htmem173)/Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-2000049
応用分野：Immunotherapy,drug screening
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系統名：C57BL/6Smoc-Tigitem1(hTIGIT)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-00053
応用分野：Immunotherapy,cancer research,drug screening
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系統名：C57BL/6Smoc-Tigitem1(hTIGIT)Ccr8em1(hCCR8)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-210426
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