SMOC has developed a set of mouse models expressing humanized immune checkpoints. These models are suitable to assess the efficacy of drugs targeting immune checkpoints in fully immunocompetent mice.
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系統名：BALB/cAnSmoc-Siglec15em2(hSIGLEC15) Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-200001
応用分野：Immunotherapy,cancer research,drug screening
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系統名：C57BL/6Smoc-Sigleceem1(hSIGLEC8)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-204983
応用分野：Immunotherapy, drug screening
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系統名：C57BL/6Smoc-Siglecfem1(hSIGLEC8)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-210033
応用分野：inmmue therapy；drug screening
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系統名：C57BL/6Smoc-Sirpatm2(hSIRPA)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-18015
応用分野：Immunotherapy,drug screening
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系統名：C57BL/6Smoc-Sirpatm2(hSIRPA)Cd47em1(hCD47)/Smoc
維持形態：Repository Live | SMOC番号：NM-HU-2000111
応用分野：Immunotherapy,cancer research,drug screening
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系統名：C57BL/6Smoc-Sirpatm2(hSIRPA)Cd47em1(hCD47)Ctla4em1(hCTLA4) Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-210368
応用分野：inmmue therapy;drug screening
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系統名：C57BL/6Smoc-Sirpatm2(hSIRPA)Cd47em1(hCD47) Pdcd1em1(hPDCD1)Smoc
維持形態：Sperm cryopreservation | SMOC番号：NM-HU-2000090
応用分野：Immune-related
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系統名：C57BL/6Smoc-Sirpatm2(hSIRPA)Cd47em1(hCD47)Pdcd1em1(hPDCD1)Cd274em1(hPD-L1)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-210358
応用分野：inmmue therapy；drug screening
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系統名：C57BL/6Smoc-Sirpatm2(hSIRPA)Cd47em1(hCD47)Pdcd1em1(hPDCD1)Cd274em2(hPD-L1)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-220029
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