SMOC has developed a set of mouse models expressing humanized immune checkpoints. These models are suitable to assess the efficacy of drugs targeting immune checkpoints in fully immunocompetent mice.
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系統名：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-SIGLEC8-IRES-EGFP-WPRE-polyA)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-KI-210137
応用分野：Fluorescent reporter Mice
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系統名：C57BL/6Smoc-Cd40em1(hCD40)Rag2em1Il2rgem1/Smoc
維持形態：Developing | SMOC番号：NM-HU-2000112
応用分野：Immunotherapy,cancer research,drug screening
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系統名：C57BL/6Smoc-Sirpaem1(hSIRPA)Cd47em1(hCD47)Rag2em1Il2rgem1/Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-2000019
応用分野：Immunotherapy,drug screening
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