SMOC has developed a set of mouse models expressing humanized immune checkpoints. These models are suitable to assess the efficacy of drugs targeting immune checkpoints in fully immunocompetent mice.
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系統名：B6.129S-Lag3tm1(hLAG3)Ctla4em1(hCTLA4)/Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-190018
応用分野：Immune-related
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系統名：C57BL/6Smoc-Lair1em2(LAIR1)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-2000011
応用分野：Immunotherapy,cancer research,drug screening
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系統名：C57BL/6Smoc-Lair1em2(LAIR1)Pdcd1em1(hPDCD1)Cd274em1(hPD-L1)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-220040
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系統名：C57BL/6Smoc-Marcoem1(hMARCO)/Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-2000029
応用分野：Immunotherapy,drug screening
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系統名：C57BL/6Smoc-Nkg2tm1(hNKG2A)Cd94tm1(hCD94)/Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-2000016
応用分野：Immunotherapy,drug screening
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