SMOC has developed a set of mouse models expressing humanized immune checkpoints. These models are suitable to assess the efficacy of drugs targeting immune checkpoints in fully immunocompetent mice.
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系統名：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-hFcRn)Fcgrtem1/Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-00109
応用分野：cancer research,Immunotherapy,drug screening
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系統名：C57BL/6Smoc-Fcgrtem2(hFCGRT)Smoc
維持形態：Repository Live | SMOC番号：NM-HU-190070
応用分野：Immunotherapy,cancer research,drug screening
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系統名：C57BL/6Smoc-Fcgrttm3(hFCGRT)/Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-2000032
応用分野：Immunotherapy,drug screening
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系統名：NOD-PrkdcscidFcgrtem2(FCGRT)Smoc
維持形態：Repository Live | SMOC番号：NM-HU-200006
応用分野：Immunotherapy,cancer research,drug screening
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系統名：C57BL/6Smoc-Gdf15em1(hGDF15)Pdcd1em1(hPDCD1)Cd274em1(hPD-L1)Smoc
維持形態：Sperm cryopreservation | SMOC番号：NM-HU-220151
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系統名：C57BL/6Smoc-Icosem1(hICOS)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-00052
応用分野：Immunotherapy,cancer research,drug screening
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系統名：C57BL/6Smoc-Icosem2(hICOS)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-190030
応用分野：Immunotherapy,cancer research,drug screening
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系統名：BALB/cAnSmoc-Icosem1(hICOS)/Smoc
維持形態：Sperm cryopreservation | SMOC番号：NM-HU-2000046
応用分野：Immunotherapy,drug screening
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系統名：C57BL/6Smoc-Icoslem1(hICOSLG) Icosem1(hICOS)/Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-18018
応用分野：Immunotherapy,cancer research,drug screening
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