SMOC has developed a set of mouse models expressing humanized immune checkpoints. These models are suitable to assess the efficacy of drugs targeting immune checkpoints in fully immunocompetent mice.
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系統名：C57BL/6Smoc-Cd40em(hCD40)Tnfrsf4em(hTNFRSF4)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-220645
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系統名：C57BL/6Smoc-Cd40em1(hCD40)Pdcd1em1(hPDCD1)Cd274em1(hPD-L1)/Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-210406
応用分野：inmmue therapy; drug screening
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系統名：C57BL/6Smoc-Cd40lgtm1(hCD40L)/Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-2000033
応用分野：Immunotherapy,drug screening
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系統名：BALB/cAnSmoc-Cd40lgtm1(hCD40L)/Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-2000052
応用分野：Immunotherapy,drug screening
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系統名：C57BL/6Smoc-Cd52em1(hCD52)/Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-2000058
応用分野：Immunotherapy,drug screening
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