SMOC has developed a set of mouse models expressing humanized metabolic targets. These models are suitable to assess the efficacy of drugs targeting metabolic pathways proteins in fully immunocompetent mice.
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系統名：C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-Frt-2xpolyA-CAG-Frt-LSL-hPNPLA3 I148M-IRES-GFP-wpre-polyA)Smoc
維持形態：Repository Live | SMOC番号：NM-KI-200013
応用分野：rs738409：148 isoleucine to Methionine protein variant,I148M.Non-alcoholic fatty liver and hepatitis B cirrhosis research.
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系統名：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-FRT-LSL- SOD1(G94A)-IRES-EGFP-WPRE-pA)Smoc
維持形態：Sperm cryopreservation | SMOC番号：NM-KI-200263
病気の予測：amyotrophic lateral sclerosis type 1
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系統名：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-V5-TERT-IRES-Luciferase-2A-EGFP-WPRE-pA)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-KI-18035
応用分野：Telomerase
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系統名：C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-Frt-2xpolyA-CAG-Frt-LSL-TM6SF2-IRES-GFP-WPRE-PA)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-KI-200017
応用分野：Non-alcoholic fatty liver disease
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系統名：FVB-Gt(ROSA)26Sorem1(pAPOE-CYP3A4)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-KI-18032
応用分野：metabolism
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系統名：FVB-Gt(ROSA)26Sorem1(Gut-CYP3A4-IRES-tdTomato)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-KI-18033
応用分野：metabolism
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