SMOC has developed a set of mouse models expressing humanized metabolic targets. These models are suitable to assess the efficacy of drugs targeting metabolic pathways proteins in fully immunocompetent mice.
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系統名：C57BL/6Smoc-Mefvem1(hMEFV-V726A)Smoc
維持形態：Sperm cryopreservation | SMOC番号：NM-KI-200221
病気の予測：familial Mediterranean fever
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系統名：C57BL/6Smoc-Tgtn(pAlb-hAPOB-WPRE-pA)1Smoc
維持形態：Repository Live | SMOC番号：NM-TG-234136
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系統名：C57BL/6Smoc-Tgtn(pAlb-hLPA-3’UTR-pA)1Smoc
維持形態：Repository Live | SMOC番号：NM-TG-231782
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系統名：C57BL/6Smoc-Tg(pAlb-hLPA-WPRE-pA)1Smoc
維持形態：Sperm cryopreservation | SMOC番号：NM-TG-232196
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系統名：C57BL/6Smoc-Gt(ROSA)26Sorem1(R26-CAG-Loxp-Stop-Loxp-hAR-IRES-EGFP-WPRE-pA)Smoc
維持形態：Sperm cryopreservation | SMOC番号：NM-KI-215053
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系統名：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-loxp-STOP-loxp-BCR-ABL-IRES-Luciferase-2A-tdTomato-WPRE-polyA)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-KI-190127
応用分野：Chronic Myelocytic Leukemia(CML) research
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系統名：C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-polyA-CAG-LSL-ETV6-NTRK3-IRES-luc-2A-tdTomato-WPRE-polyA)Smoc
維持形態：Sperm cryopreservation | SMOC番号：NM-KI-190107
応用分野：cancer research
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系統名：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-IDH1(R132H)-IRES-Luciferase-2A-tdTomato)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-KI-190074
応用分野：cancer research
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系統名：C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-FRT-2xpA-CAG-FRT-loxp-STOP-loxp-MLL-AF9-IRES-Luciferase-2A-tdTomato -WPRE-polyA)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-KI-190114
応用分野：Acute myelogenous leukemia model
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