SMOC has developed a set of mouse models expressing humanized cytokines. These models are suitable to assess the efficacy of drugs targeting cytokines in fully immunocompetent mice.
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系統名：BALB/cAnSmoc-Tnfsf15em1(hTNFSF15)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-220602
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系統名：C57BL/6Smoc-Tgtn(hTNFa promoter-hTNFa-pA)Smoc
維持形態：Repository Live | SMOC番号：NM-TG-200004
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系統名：C57BL/6Smoc-Tnfrsf23tm(hTNFRSF10C)Smoc
維持形態：Sperm cryopreservation | SMOC番号：NM-HU-230344
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系統名：C57BL/6Smoc-Tslptm2(hTSLP)/Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-2000064
応用分野：Asthma research；drug screening
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系統名：C57BL/6Smoc-Tslptm2(hTSLP)Il17rtm1(hIL17R)/Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-200269
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系統名：NOD.Cg-PrkdcscidIl2rgem1SmocIl15em1(hIL15)Smoc
維持形態：Repository Live | SMOC番号：GM-NVG-210001
応用分野：Immunotherapy,cancer research,drug screening
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系統名：C57BL/6Smoc-Gt(ROSA)26Sorem1(pCAG-FRT-loxp-stop-loxp-hCD63-copGFP-6xHis-WPRE-polyA-FRT)Smoc
維持形態：Sperm cryopreservation | SMOC番号：NM-KI-200044
応用分野：Exosome tracing model
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系統名：C57BL/6Smoc-Gt(ROSA)26Sortm(CAG-Loxp-Stop-Loxp-Kozak-hIL2 signal peptide-hIL15-Flag-IRES-EGFP-polyA)Smoc
維持形態：Sperm cryopreservation | SMOC番号：NM-KI-220130
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