Point mutant knockin mouse model is a mouse in which one or more nucleotides are replaced by mutant nucleotides in the genome. This may result in amino acid changes within the protein sequence, and transcription terminated, thereby significantly affecting the normal function of the protein. Point mutation mouse models are widely used to study the role of specific nucleotides or amino acids in genetic elements or proteins, as well as to mimic human genetic diseases.
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系統名：C57BL/6Smoc-Kitem2(V831M)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-KI-190023
応用分野：hematopoieticstem cell
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系統名：NOD-PrkdcscidKitem1(V831M)Smoc
維持形態：Sperm cryopreservation | SMOC番号：NM-KI-200316
応用分野：Hematopoieticstem cell
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系統名：C57BL/6Smoc-Krasem4(LSL-G12D)Smoc
維持形態：Repository Live | SMOC番号：NM-KI-190003
病気の予測：squamous cell carcinoma, prostate cancer, pancreatic carcinoma, neurofibromatosis, pancreatic ductal adenocarcinoma, juvenile myelomonocytic leukemia, urinary bladder cancer, ovarian cancer
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系統名：C57BL/6Smoc-Krastm(Rox-Stop-Rox-G12D)Smoc
維持形態：Sperm cryopreservation | SMOC番号：NM-KI-210436
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系統名：C57BL/6Smoc-Latem1(Y136F）Smoc
維持形態：Repository Live | SMOC番号：NM-KI-200249
病気の予測：IgG4-related disease
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系統名：C57BL/6Smoc-Ldlrem1(C223R)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-KI-00043
応用分野：Metabolic and cardiovascular disease research
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系統名：BALB/cAnSmoc-Lepem(R105X)Smoc
維持形態：Sperm cryopreservation | SMOC番号：NM-KI-230476
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系統名：B6.129S-Leprtm1Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-KI-00001
応用分野：Leptin resistance,insulin resistance,obesity,and type 2 diabetes etc.
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系統名：C57BL/6Smoc-Lmnatm1(G609G)Smoc
維持形態：Sperm cryopreservation | SMOC番号：NM-KI-200284
病気の予測：progeria
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