人类疾病相关小鼠模型，可用于研究基因在疾病中的作用、疾病遗传或发病机制等。
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系統名：C57BL/6Smoc-Nf2tm1(flox)Smoc
維持形態：Sperm cryopreservation | SMOC番号：NM-CKO-200017
病気の予測：renal cell carcinoma, neurofibromatosis, otitis media, thyroid gland cancer
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系統名：B6;129S-Nipbltm1(flox)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-CKO-00067
応用分野：Cornelia de Lange syndrome
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系統名：C57BL/6Smoc-Nos1em1Smoc
維持形態：Sperm cryopreservation | SMOC番号：NM-KO-240406
病気の予測：hypertrophic cardiomyopathy, nephrogenic diabetes insipidus, achalasia, hypertrophic pyloric stenosis
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系統名：C57BL/6Smoc-Nos3em1Smoc
維持形態：Repository Live | SMOC番号：NM-KO-18022
病気の予測：hypertrophic cardiomyopathy, nephrogenic diabetes insipidus, essential hypertension, persistent fetal circulation syndrome
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系統名：C57BL/6Smoc-Notch3em1(R170C)Smoc
維持形態：Sperm cryopreservation | SMOC番号：NM-KI-200254
病気の予測：CADASIL 1
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系統名：C57BL/6Smoc-Npc1em2(flox)Smoc
維持形態：Sperm cryopreservation | SMOC番号：NM-CKO-200070
病気の予測：Niemann-Pick disease
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系統名：C57BL/6Smoc-Nphs2em1(A286V)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-KI-200278
病気の予測：hereditary glomerular disease
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系統名：C57BL/6Smoc-Nphs2em1(R231Q)Smoc
維持形態：Sperm cryopreservation | SMOC番号：NM-KI-200277
病気の予測：hereditary glomerular disease
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系統名：C57BL/6Smoc-Npy1Rem1Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-KO-190999
病気の予測：obesity
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