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Models

About 42,575 results
マウス

Rorc-2A-tdTomato-2A-DTR

系統名：C57BL/6Smoc-Rorcem(T2A-tdTomato-P2A-DTR)Smoc
維持形態：Repository Live | SMOC番号：NM-KI-204991
表現型データ：No

T2A-tdTomato-P2A-DTR expression cassette was knocked into the Rorc gene .

マウス

hCD40/hPD-1/hPD-L1

系統名：C57BL/6Smoc-Cd40em1(hCD40)Pdcd1em1(hPDCD1)Cd274em1(hPD-L1)/Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-210406
表現型データ：No

hPD-1/hPD-L1(NM-HU-00100) was crossed with hCD40（NM-HU-00076）to generate hCD40/hPD-1/hPD-L1 mice

マウス

hPVRL2

系統名：C57BL/6Smoc-Nectin2tm1(hNECTIN2)/Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-2000084
表現型データ：Yes

The endogenous mouse Nectin2 gene was replaced by human PVRL2 gene.

マウス

Alpl-KO

系統名：C57BL/6Smoc-Alpltm1Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-KO-18058
表現型データ：Yes

This Alpl knockout mouse model was obtained by knocking out the exon 3-4 region of the Alpl gene.

マウス

Hopx-2A-DreERT2

系統名：C57BL/6Smoc-Hopxem1(2A-DreERT2)Smoc
維持形態：Sperm cryopreservation | SMOC番号：NM-KI-190035
表現型データ：Yes

A 2A-DreERT2 expression cassette was knocked into the Hopx gene stop codon site.

マウス

Lyz2-2A-CreERT2

系統名：C57BL/6Smoc-Lyz2em1(2A-CreERT2-WPRE-pA)Smoc
維持形態：Repository Live | SMOC番号：NM-KI-18018
表現型データ：Yes

A 2A-CreERT2-WPRE-pA coexpression cassette is inserted befor the stop codon of mouse Lyz2 gene via homologous recombination to establish a tamoxifen inducible Lyz2-CreERT2 tool stain. This strain can be used to knockout target gene in Lyz2+ cells after tamoxifen treatment when crossed with mice which carry loxp sites flanking target gene.

マウス

hTIGIT(3)

系統名：C57BL/6Smoc-Tigittm3(hTIGIT)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-200244
表現型データ：Yes

The endogenous mouse Tigit gene was replaced by human TIGIT gene. While hTIGIT(Stock No.NM-HU-00053) mice function similarly to hTIGIT（3） mice ,for more detailed information please contact our technical advisor.

マウス

Col1a1-TRE3G-dCas9-VPR-EGFP

系統名：C57BL/6Smoc-Col1a1em1(TRE3G-dCas9-VPR-eGFP-pA)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-KI-00123
表現型データ：No

These mice harbor a TRE3G-dCas9-VPR(VP64-p65-Rta)-eGFP-pA tetracycline-controlled transcriptional activation cassette in mouse Col1a1 loci. This strain can be used in CRISPR mediated target gene transcriptional activation (CRISPRa).

マウス

Isl1-CreERT2

系統名：C57BL/6Smoc-Isl1em1(CreERT2) Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-KI-00013
表現型データ：Yes

CreERT2 was inserted at the start codon (ATG site). The KI mice have a tamoxifen-inducible cre-mediated recombination system.

マウス

Axin2-CreERT2

系統名：C57BL/6Smoc-Axin2em1(CreERT2-pA)Smoc
維持形態：Developing | SMOC番号：NM-KI-200109
表現型データ：Yes

A CreERT2-pA expression cassette was knocked into the Axin2 gene start codon site. As Axin2 is an intracellular protein, it is essential for identifying a surface marker for stem cell purification. When these Axin2-CreERT2 mice are bred with mice containing a loxP-flanked sequence of interest, tamoxifen-inducible, Cre-mediated recombination will result in deletion of the flanked sequences in Axin2 expressing cells.

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