hIL1A

系統名

C57BL/6Smoc-Il1atm1(hIL1A)Smoc

SMOC番号

NM-HU-215071

維持形態

Embryo cryopreservation

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遺伝子の概要

Gene Symbol
Il1a

説明

The endogenous mouse Il1a gene was replaced by human IL1A gene.

表現型データ

image.png

Fig.1 Detection of IL1A expression in spleen and lung by RT-PCR. 

Wild type: only one band at 324 bp with primers F1/R1(mIl1a);

Homozygous: only one band at 265 bp with primers F2/R2(hIL1A).

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

image.png

Fig.2 Detection of hIL1A expression in bone marrow by ELISA (n=3). 

Abbr.  WT, wild type; HO, homozygous; N.D. not detected.

Note.  Monocytes derived from bone marow were stimulated with LPS in vitro for 24h.


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