hPD-1/hCTLA-4(BALB/c)

系統名

BALB/cAnSmoc-Pdcd1em1(hPDCD1)Ctla4em1(hCTLA4)Smoc

SMOC番号

NM-HU-200277

維持形態

Repository Live

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遺伝子の概要

Gene Symbol

Synonyms

PD-1， Pdc1， Ly101，Cd152， Ly-56， Ctla-4

NCBI ID

18566，12477

MGI ID

104879，88556

Ensembl ID

ENSMUSG00000026285，ENSMUSG00000026011

Pubmed

Human Ortholog

PD-1，CTLA4

説明

hPD-1(NM-HU-190079) was crossed with hCTLA4(2)(NM-HU-190078)to generate hPD-1/hCTLA4 mice

表現型データ

1.png

Fig 1.In vivo efficacy study in PD1 & CTLA4 humanized mice. Keytruda, Opdico or Yervoy can inhibit the growth of CT26-hCD274 xenografts. The above data indicated that the hPD1/hCTLA4 humanized mouse is an effective model for antineoplastic drug screening.

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