Nkx3-1-IRES-Cre

系統名

C57BL/6JSmo-Nkx3-1em1(IRES-iCre)Smoc

SMOC番号

NM-KI-200171

維持形態

Sperm cryopreservation

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遺伝子の概要

Gene Symbol
Nkx3-1

Synonyms

Bax; NKX3A; NKX3.1; Nkx-3.1; bagpipe

Chromosome

14

NCBI ID

18095

MGI ID

97352

Ensembl ID

ENSMUSG00000022061

Pubmed

Nkx3-1

Human Ortholog

NKX3-1

説明

A IRES-iCre expression cassette was knocked into the Nkx3-1 gene stop codon site. Nkx3-1 (NK3 homeobox 1) encodes prostate-specific homeodomain protein. The gene product is a key element in protecting prostate epithelial cells from DNA damage. This strain is useful for studying prostate.
応用分野：Cre recombinase tool; Prostate

表現型データ

image.png

Fig. 1 Cre-mediated recombination in the prostate of Nkx3-1Cre/+; Rosa26tdTomato/+ mouse. TdTomato(red) expression can be detected in the atrium derived from Nkx3-1Cre/+; Rosa26tdTomato/+ mouse.

image.png

Fig. 2 Detection of tdTomato(red) in various tissues of Nkx3-1Cre/+; Rosa26tdTomato/+ mice. Cre-mediated recombination can be detected in some cells of the prostate, brain, liver, kidney, salivary gland, stomach, thymus, colon, muscle, pancreas, brown fat, intestine and in individual cells of the spleen. (For more detailed information please contact our technical advisor.)


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