Krt5-IRES-CreERT2

系統名

C57BL/6Smoc-Krt5em1(IRES-CreERT2)Smoc

SMOC番号

NM-KI-200168

維持形態

Sperm cryopreservation

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遺伝子の概要

Gene Symbol
Krt5

Synonyms

K5; CK5; Tfip8; Krt2-5; AW146334; 3300001P10Rik

NCBI ID

110308

MGI ID

96702

Ensembl ID

ENSMUSG00000061527

Pubmed

Krt5

Human Ortholog

KRT5

説明

A IRES-CreERT2 expression cassette was knocked into the Krt5 gene stop codon site.
応用分野：Cre recombinase tool

表現型データ

Krt5-IRES-CreERT2-1 - 副本.png

Fig. 1 Detection of tdTomato (red) in the epidermis and hair follicle of Krt5CreERT2/+; Rosa26tdTomato/+  mouse. CreERT2-mediated recombination in the epidermis and hair follicle of Krt5CreERT2/+; Rosa26tdTomato/+ mouse. Some leakiness were detected in the epidermis and hair follicle prior to tamoxifen exposure.

Krt5-IRES-CreERT2-2 - 副本.png

Fig. 2 Detection of tdTomato (red) in various tissues of Krt5CreERT2/+; Rosa26tdTomato/+ mice. 

CreERT2-mediated recombination in the brown fat and submandibular gland can be induced by tamoxifen. Some leakiness were detected in the skin，eyes and testis prior to tamoxifen exposure.

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