Il13-IRES-Cre

系統名

C57BL/6Smoc-Il13em1(IRES-iCre)Smoc

SMOC番号

NM-KI-200166

維持形態

Sperm cryopreservation

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説明

A IRES-iCre expression cassette was knocked into the Il13 gene stop codon site. This gene encodes a multifunctional cytokine. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing cre. This cytokine participates in the regulation of immune response, inflammatory response and hematopoietic process.
応用分野：Cre recombinase tool; IL13-expressing cell

表現型データ

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Fig. 1 Cre-mediated recombination in the thymus of Il13Cre/+; Rosa26tdTomato/+ mouse. TdTomato(red) expression can be detected in  individual cells of the thymus derived from Il13Cre/+; Rosa26tdTomato/+ mouse.

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Fig. 2 Cre-mediated recombination in the spleen of Il13Cre/+; Rosa26tdTomato/+ mouse. TdTomato(red) expression can be detected in  the spleen derived from Il13Cre/+; Rosa26tdTomato/+ mouse.

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Fig. 3 Detection of tdTomato(red) in various tissues of  Il13Cre/+; Rosa26tdTomato/+ mice. Cre-mediated recombination can be detected in some cells of the thymus and spleen and in individual cells of the stomach and testis. Tdtomato expression can not be observed in the heart. (For more detailed information please contact our technical advisor.)


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