Il17a-Cre

系統名

C57BL/6Smoc-Il17aem1(iCre-polyA(SV40))Smoc

SMOC番号

NM-KI-200137

維持形態

Repository Live

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遺伝子の概要

Gene Symbol
IL17A

Synonyms

Il17; Ctla8; IL-17; Ctla-8; IL-17A

NCBI ID

16171

MGI ID

107364

Ensembl ID

ENSMUSG00000025929

Pubmed

IL17A

Human Ortholog

IL17A

説明

A iCre-polyA expression cassette was knocked into the Il17a gene start codon site. This gene encodes a pro-inflammatory cytokine that is a member of the interleukin-17 family. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing cre. This strain may be useful for studying autoimmune inflammatory diseases such as rheumatoid arthritis, psoriasis and multiple sclerosis.
応用分野：Cre recombinase tool; T helper cell

表現型データ

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Fig 1. Cre mediated recombination in lung of Il17aCre/+;Rosa26tdTomato/+ mouse. 

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Fig 2. Cre mediated recombination in mesenteric lymph nodes of Il17aCre/+;Rosa26tdTomato/+ mouse. 

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