Cpa3-2A-CreERT2

系統名

C57BL/6JSmo-Cpa3em2(2A-CreERT2-WPRE-polyA)Smoc

SMOC番号

NM-KI-200005

維持形態

Repository Live

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遺伝子の概要

Gene Symbol
Cpa3

説明

A 2A-CreERT2-WPRE-polyA expression cassette was knocked into the Cpa3 gene stop codon site.
応用分野:Cre recombinase tool

表現型データ

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Fig1. Cre mediated recombination in skin of Cpa3CreERT2/+;Rosa26tdTomato/+ mouse.

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Fig2. Cre mediated recombination in stomach of Cpa3CreERT2/+;Rosa26tdTomato/+ mouse.

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Fig3. Detection of tdTomato(red) in various tissues of Cpa3CreERT2/+;Rosa26tdTomato/+ mouse. Expression tissues include: skin and stomach. A few cells expressed in: salivary gland and uterus. No obvious positive signals were observed in the brain, pituitary gland, retina, heart, lungs, liver, brown fat, muscles, kidneys, pancreas, small intestine, large intestine, spleen and thymus.(61-days old, female) (For more detailed information please contact our technical advisor.)

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Fig4. Detection of mast cells in stomach and skin of Cpa3CreERT2/+;Rosa26tdTomato/+ mouse. No reduction in mast cells was observed in the skin of Cpa3CreERT2/+;Rosa26tdTomato/+ induced with Tamoxifen.


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