hCD79B

系統名

C57BL/6JSmo-Cd79btm2(hCD79B )Smoc

SMOC番号

NM-HU-2000012

維持形態

Embryo cryopreservation

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遺伝子の概要

Gene Symbol
CD79b

説明

The endogenous mouse Cd79b gene was replaced by human CD79B gene.
応用分野:Immunotherapy,cancer research,drug screening

表現型データ

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Fig.1 Detection of CD79B expression on B cells in blood and spleen of WT C57BL/6 mice and HO hCD79B mice by FACS. Leukocytes were collected from wild-type C57BL/6 mice (female, 7 weeks old) and homozygous hCD79B humanized mice (male, 9 weeks old), and analyzed by flow cytometry with anti-mCD79B and anti-hCD79B. hCD79B was exclusively detectable in hCD79B humanized mice but not in wild-type mice. hCD79B was exclusively detectable on B cells in hCD79B humanized mice, whereas mCD79B was exclusively detectable on B cells in wild-type C57BL/6 mice.


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