hTIGIT/hPVR

系統名

C57BL/6Smoc-Tigitem1(hTIGIT)Pvrem1(hPVR)Smoc

SMOC番号

NM-HU-2000091

維持形態

Embryo cryopreservation

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遺伝子の概要

Gene Symbol

Synonyms

Vstm3，PVS， mE4， HVED， Taa1， CD155， Tage4， necl-5， D7Ertd458e， 3830421F03Rik

NCBI ID

100043314，52118

MGI ID

3642260，107741

Ensembl ID

ENSMUSG00000071552，ENSMUSG00000040511

Pubmed

Human Ortholog

TIGIT，PVR

説明

These mice are obtained through breeding of two single gene humanized mice.
応用分野：Immunotherapy,cancer research,drug screening

表現型データ

TIGIT.png

Fig.1 Splenocytes from homozygous TIGIT&PVR mice were analyzed by flow cytometry after activation. mTIGIT+ cells were detectable in wild type (WT) C57BL/6, while hTIGIT+ cells were detectable in the homozygous TIGIT&PVR mice. 

PVR.png

Fig.2 Splenocytes from homozygous TIGIT&PVR mice were analyzed by flow cytometry after activation. mPVR+ cells were detectable in wild type (WT) C57BL/6, while hPVR + cells were detectable in the homozygous TIGIT&PVR mice.

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