hIL2RB

系統名

C57BL/6Smoc-Il2rbtm1(hIL2RB)/Smoc

SMOC番号

NM-HU-2000055

維持形態

Embryo cryopreservation

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説明

The endogenous mouse Il2rb gene was replaced by human IL2RB gene.
応用分野：Cytokine humanization model；drug screening

表現型データ

NM-HU-2000055 hIL2RB.png

Fig1. Analysis of IL2RB gene expression in the liver by RT-PCR.

Mouse Il2rb mRNA was detectable by P1/2(511bp), human IL2RB mRNA was detectable by P1/3(513bp), 

M:100bp Plus DNA ladder from Transgen (BM311). The heterozygous KI mouse expresses both human IL2RB and mouse Il2rb in the liver.

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