hAPOE3

系統名

C57BL/6JSmo-Apoetm3(hAPOE3)Smoc

SMOC番号

NM-HU-190003

維持形態

Repository Live

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遺伝子の概要

Gene Symbol
Apoe

説明

This APOE3 humanized mouse model was established by replacing the mouse Apoe gene coding exons and introns with the human APOE3 corresponding sequence by homologous recombination.
応用分野:Cardiovascular disease

表現型データ

Validation data

Apoe3-2.png

Fig1. Genotyping of WT 、KO &  Humanized mice by PCR.

Primer P1/2 Wild type = 342 bp

Primer P3/4 mutant = 332 bp

M:100bp Plus DNA ladder.

image.png

Fig2. Western blot analysis of  APOE3 protein from  WT、KO & Humanized mice. 


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