hCCL4

系統名

C57BL/6Smoc-Ccl4em1(hCCL4)/Smoc

SMOC番号

NM-HU-210013

維持形態

Embryo cryopreservation

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遺伝子の概要

Gene Symbol
Ccl4

Synonyms

Act-2; Mip1b; Scya4; MIP-1B; AT744.1

NCBI ID

20303

MGI ID

98261

Ensembl ID

ENSMUSG00000018930

Pubmed

Ccl4

Human Ortholog

CCL4

説明

The endogenous mice Ccl4 gene was replaced by human CCL4 gene
応用分野：drug screening

表現型データ

image.png

Fig1. Detection of CCL4 expression in small intestine, spleen and  thymus by RT-PCR. Wild type: only one band at 242 bp with primers F1/R1(mCcl4); Homozygous: only one band at 144 bp with primers F2/R2(hCCL4); Abbr. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.

image.png

Fig 2. Detection of hCCL4 expression in plasma by ELISA. Abbr. HO, homozygous; HE, heterozygous; WT, wild type. Note. hCCL4 and C57BL/6 mice were i.p. injected with LPS(20mg/kg) for 6h.

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