hC1S
系統名
C57BL/6Smoc-C1s1em1(hC1S)/Smoc
SMOC番号
NM-HU-2000077
維持形態
Repository Live
遺伝子の概要
Gene Symbol
C1s1
説明
表現型データ
Fig1. Detection of C1S1 expression in bladder by RT-PCR. Wild type: only one band at 396 bp with primers F1/R1(mC1s1); Homozygous: only one band at 294 bp with primers F2/R2(hC1S1); Abbr. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.
Fig2. Detection of hC1S1 expression in serum by ELISA (n=8). Abbr. HO, homozygous; WT, wild type.
Fig3. Detection of mC3 and mC5 expression in serum hC1S1 mice by ELISA (n=3). Abbr. HO, homozygous; WT, wild type.
Fig .4 Detection of classical complement pathway activity in hC1S mice by ELISA.
Abbr. HO, homozygous; WT, wild type; PC, Postive Control; NC, Negative Control. Unpaired t test were used, n.s. p>0.05.
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On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
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