hC5AR1/C5AR2

系統名

C57BL/6Smoc-C5ar1tm1(hC5AR1)C5ar2tm1(hC5AR2)/Smoc

SMOC番号

NM-HU-2000018

維持形態

Repository Live

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遺伝子の概要

Gene Symbol
C5AR1

Synonyms

C5aR; C5r1; Cd88; D7Msu1

NCBI ID

12273

MGI ID

88232

Ensembl ID

ENSMUSG00000049130

Pubmed

C5AR1

Human Ortholog

C5AR1

Gene Symbol
C5AR2

Synonyms

C5L2; Gpr77; E030029A11Rik

NCBI ID

319430

MGI ID

2442013

Ensembl ID

ENSMUSG00000074361

Pubmed

C5AR2

Human Ortholog

C5AR2

説明

The endogenous mouse C5ar1 and C5ar2 gene was replaced by human C5AR1 and hC5AR2 gene.
応用分野：Immunotherapy,drug screening

表現型データ

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Fig1. Detection of C5AR1 expression on myeloid cells in blood in homozygous hC5AR1 mice. 

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Fig2. Detection of C5AR1 expression on myeloid cells in bone morrow in homozygous hC5AR1 mice. 

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Fig3. Detection of hC5AR2 expression on myeloid cells in heterozygous hC5AR1/hC5AR2 mice. (Note: Anti-human C5L2 (C5AR2) antibody was cross-binding with mouse C5AR2)

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