hADORA2A
系統名
C57BL/6Smoc-Adora2atm1(hADORA2A)Smoc
SMOC番号
NM-HU-215061
維持形態
Repository Live
遺伝子の概要
Gene Symbol
Adora2a
説明
表現型データ
Fig1. Detection of ADORA2A expression in thymus and spleen by RT-PCR. Wild type: only one band at 184 bp with primers F1/R1 (mAdora2a); Homozygous: only one band at 234 bp with primers F2/R2 (hADORA2A); Abbr. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.
Fig2. Detection of hADORA2A expression in Myeloid cells and activated T cells in hADORA2A KI mice. Note. Splenocytes from C57BL/6 and homozygous hADORA2A mice were stimulated with anti-mCD3 antibody in vitro. The anti-human ADORA2A antibody cross-reacted with mADORA2A and humanized ADORA2A.
Fig3. Detection of hADORA2A expression in activated B cells and NK cells in hADORA2A KI mice. Note. Splenocytes from C57BL/6 and homozygous hADORA2A mice were stimulated with anti-mCD3 antibody in vitro. The anti-human ADORA2A antibody cross-reacted with mADORA2A and humanized ADORA2A.
Fig4. Detection of mA2AR expression in hippocampus(CA3) in C57BL/6 mice by IHC. Abbr. HO/HO, homozygous; +/+, wild type. Note. The anti-mouse ADORA2A Antibody cross-reacted with mADORA2A and humanized ADORA2A.
Fig5. Detection of hA2AR expression in hippocampus(CA3) in HO hADORA2A KI mice by IHC. Abbr. HO/HO, homozygous; +/+, wild type. Note. The anti-human ADORA2A Antibody cross-reacted with mADORA2A and humanized ADORA2A.
あなたも好きかも
On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
詳細Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.
詳細